Oligonucleotide Synthesis Market Size, Share, Trends, Growth 2032

Oligonucleotide Synthesis Market: Overview

The global oligonucleotide synthesis market size was worth around USD 9.03 billion in 2023 and is predicted to grow to around USD 34.34 billion by 2032 with a compound annual growth rate (CAGR) of roughly 16.00% between 2024 and 2032.

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The report covers a forecast and an analysis of the oligonucleotide synthesis market on a global and regional level. The study provides historical data for 2018 and 2022 along with a forecast from 2024 to 2032 based on revenue (USD Billion). The study includes the drivers and restraints of the oligonucleotide synthesis market along with the impact they have on the demand over the forecast period. Additionally, the report includes the study of opportunities available in the oligonucleotide synthesis market on a global level.

Oligonucleotide Synthesis Market: Growth Drivers

Small fragments of nucleic acids that are synthesized via enzyme chemistry and genetic engineering are known as oligonucleotides. These are mainly used in laboratories for diagnostics, therapeutics, and in academic and industrial research. Oligonucleotides are also used for initial screening of target validation and drug production. The process of oligonucleotides synthesis occurs either individually via DNA synthesizers or commercially to provide services for various end-users or self-consumption. The improvement in oligonucleotide synthesis, automation, and amplification has completely revolutionized the biological research domain. Nowadays, it is possible to get customizations and specific sequences online easily and at any required time. Companies are focusing on improving their services via technology improvisations with cost control to get more traction.

Major oligonucleotides manufacturers are expanding their businesses through collaboration with pharmaceutical manufacturers. Subsequent numbers of oligos are in a later phase of clinical trials that are targeted at various conditions, such as cardiovascular diseases, muscle dystrophies, ocular disorders, and majorly cancer. This, in turn, has further anticipated the regulatory approvals for multiple oligonucleotide-based therapies.

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The oligonucleotides synthesis market is likely to benefit from the constant growth of gene editing and genomics markets, as there are a large number of advancements related to genetic tools for simplifying the synthesis of oligonucleotide process. Furthermore, the improvements in patient response systems are also generating a multitude of data, thereby, furthering the oligonucleotide synthesis market in the future.

In order to give the users of this report a comprehensive view of the oligonucleotide synthesis market, we have included a competitive landscape and an analysis of Porter’s Five Forces model for the market. The study encompasses a market attractiveness analysis, wherein all the segments are benchmarked based on their market size, growth rate, and general attractiveness.

The report provides company market share analysis to give a broader overview of the key market players. In addition, the report also covers key strategic developments of the market including acquisitions & mergers, new product launches, agreements, partnerships, collaborations & joint ventures, research& development, and regional expansion of major participants involved in the market on a global and regional basis.

Oligonucleotide Synthesis Market: Segmentation

The global market for oligonucleotide synthesis is segmented on the basis of the offering, application, and end-user.

By offering, the oligonucleotide synthesis market is segmented into equipment, reagents and consumables, and synthesized oligonucleotides. The synthesized oligonucleotides market is further divided into product and services. The products segment includes large-scale synthesis oligonucleotides, probes, primers, linkers and adaptors, intermediate-scale synthesis oligonucleotides, and others. The services segment includes custom/specialty oligonucleotides (modified and non-modified oligonucleotides) and pre-designed oligonucleotides.

By application, this global market includes research, therapeutics, and diagnostics. The research segment includes polymerase chain reaction, qPCR, next-generation sequencing, and others. The therapeutics segment includes antisense oligonucleotides, RNAi, nucleic acid aptamers, and immunotherapy applications.

By end-user, the market includes pharmaceutical and biotechnology companies, diagnostic laboratories, academic research institutes, and others.

Oligonucleotide Synthesis Market : Report Scope

Oligonucleotide Synthesis Market : Regional Analysis

The regional segmentation includes the current and forecast demand for North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa with its further divided into major countries.

By region, the global oligonucleotide synthesis market includes North America, Latin America, Asia Pacific, Europe, and the Middle East and Africa. North America is anticipated to dominate the market for oligonucleotide synthesis and hold a major share of the oligonucleotide synthesis market over the forecast timeline. This regional dominance can be attributed to the growing prevalence of genetic diseases and the subsequent demand for new and advanced drugs. The Asia Pacific and European regions are likely to register a rise in their market valuation over the estimated timeframe.

The Asia Pacific oligonucleotide synthesis market is projected to be driven by the strong presence of innumerable companies offering consumables and reagents for oligonucleotide synthesis and the increased need for better health outcomes, the rising prevalence of infectious and chronic diseases, and the availability of improved healthcare infrastructure in the region.

Oligonucleotide Synthesis Market: Competitive Analysis

The global Oligonucleotide Synthesis market is dominated by players like:

• ATD Bio Ltd
• BianoScience GmbH
• BioSpring GmbH
• Bioneer Corporation
• Bio-Synthesis, Inc
• Creative Biogene
• Dalton Pharma Services
• Eurofins Genomics
• GE
• GeneDesign, Inc
• GenScript
• IBA GmbH
• Integrated DNA Technologies, Inc
• Kaneka Eurogentec S.A.
• LGC Biosearch Technologies
• Merck KGaA
• Microsynth AG
• Syngene
• Thermo Fisher Scientific
• TriLink BioTechnologies LLC
• Twist Bioscience

This report segments the global oligonucleotide synthesis market into:

Global Oligonucleotide Synthesis Market: Offering Analysis

• Equipment
• Reagents and Consumables
• Synthesized Oligonucleotides
  • By Product
    • Primers
    • Probes
    • Large-Scale Synthesis Oligonucleotides
    • Intermediate-Scale Synthesis Oligonucleotides
    • Linkers and Adaptors
    • Others
  • By Service
    • Custom/Specialty Oligonucleotides
      • Modified
      • Non-Modified
    • Pre-Designed Oligonucleotides

Global Oligonucleotide Synthesis Market: Application Analysis

• Research
  • Polymerase Chain Reaction
  • qPCR
  • Next Generation Sequencing
  • Others
• Therapeutics
  • Antisense Oligonucleotides
  • RNAi
  • Nucleic Acid Aptamers
  • Immunotherapy Applications
• Diagnostics

Global Oligonucleotide Synthesis Market: End-User Analysis

• Academic Research Institutes
• Diagnostic Laboratories
• Pharmaceutical and Biotechnology Companies
• Others

Global Oligonucleotide Synthesis Market: Regional Analysis

• North America
  • The U.S.
• Europe
  • UK
  • France
  • Germany
• Asia Pacific
  • China
  • Japan
  • India
• Latin America
  • Brazil
• Middle East and Africa