Sample Preparation Market Size, Share, Growth Report 2030

Industry Prospective:

The global sample preparation market size was worth around USD 6.2 billion in 2021 and is predicted to grow to around USD 10.9 billion by 2030 with a compound annual growth rate (CAGR) of roughly 6.5% between 2022 and 2030. The report analyzes the global sample preparation market’s drivers, restraints/challenges, and the effect they have on the demands during the projection period. In addition, the report explores emerging opportunities in the sample preparation market.      

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Sample Preparation Market: Overview

The process of extracting or enriching analytes from sample matrices into the final analyte solution is known as sample preparation. Drawing, handling, and preparing samples by the standards of contemporary microbiology are all part of the process. It consists of biological and chemical samples for the analysis of raw materials to find undesired components in different chemical compounds. It offers greater separation in chromatography, higher throughput, easier automation, increased sensitivity, and detection of certain functional groups. The sample preparation technique is therefore widely applied across numerous industry sectors.

Key Insights

• As per the analysis shared by our research analyst, the global sample preparation market is estimated to grow annually at a CAGR of around 6.5% over the forecast period (2022-2030).
• In terms of revenue, the global sample preparation market size was valued at around USD 6.2 billion in 2021 and is projected to reach USD 10.9 billion, by 2030.
• Rapid advancement in technology and increasing emphasis on forensic testing and biodefense in developing as well as developed countries are giving a boost to the sample preparation market globally.
• Based on the product, the consumables are expected to hold a significant market share during the forecast period.
• Based on the technique, the protein preparation segment accounted for the largest revenue share in 2021.
• Based on region, North America is expected to dominate the market during the forecast period.

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Sample Preparation Market: Growth Drivers

The rapid shift from manual to automated sample preparation methods to drive market growth

The demand for automation in sample preparation equipment is being driven by the growing uptake of cutting-edge technology and strict guidelines for product development. Additional benefits of automated sample preparation include high productivity, repeatability, and traceability. Decreasing exposure to dangerous substances like ammonia, sulfuric acid, and biological laboratory samples, also decreases the dangers to the operator's health and safety. Additionally, consumers like entire framework solutions over separate workstations since they provide integration of various sample preparation tools in a single location. By reducing resource allocation for repetitive processes including sample extraction, filtration, weighing, dilution, and sample analysis, automated sample preparation increases a laboratory's productivity.

Sample Preparation Market: Restraints

High cost of equipment

Continuous technological improvements in the global sample preparation market in terms of product design and efficiency are likely to encourage producers to provide customers with up-to-date solutions. Customers are often cautious to opt for cost-intensive upgrade procedures since these lead to the degradation of investments. As a result, the high cost of equipment and end-user reluctance to invest in new equipment frequently is projected to obstruct the growth of the sample preparation market.

Sample Preparation Market: Opportunities

Rising innovation in blood collecting equipment and expanding R&D support from various government and private entities

Various government and private organizations are working on boosting research and development investment in clinical diagnostic, forensic, proteomics, and genomics research. To produce significant and accurate results, proper sample preparation is essential. Furthermore, rising R&D spending by various government and corporate entities is likely to boost the usage of sophisticated sample preparation devices over the projection period. For instance, in March 2018, the German Research Foundation (DFG) allocated US$ 17.3 million to four new sequencing labs in Germany. The funds will be utilized to do research in the field of next-generation sequencing. Thus, providing a lucrative opportunity for global sample preparation market expansion.

Sample Preparation Market: Challenges

Risk of discovering unknown variance  

One of the most serious issues with the NGS approach is that it increases the likelihood of discovering mutations that have no evident effect on clinical relevance. Because a large number of genes are being examined, many unexpected results will probably be discovered. Some of these findings may be risk factors for additional diseases or other variations. Professionals with extensive experience, such as molecular pathologists and clinical geneticists, are required to determine how harmful the discovered variations are and to distinguish between those that are and are not dangerous.

Sample Preparation Market: Segmentation

The global sample preparation market is segmented based on product, technique, application, end-user, and region

Based on the product, the global market is bifurcated into instruments, consumables, and kits. The consumables are expected to hold a significant market share during the forecast period. Compared to instruments, consumables are more often used and less subject to the seasonality of market and industry cycles. For instance, with a favorable effect on segment growth, PacBio reported a 22.16% increase in consumables sales from USD 10.4 million the year before to USD 12.7 million. On the other hand, during the anticipated period, it is projected that the instruments segment will continue to rise steadily. Because instruments have a longer lifespan and cost more than consumables, end customers rarely buy them. Incorporating precise quality tools is crucial for end users to get rid of any potential sample contamination that can interfere. For instance, the Bioteke Corporation's nucleic acid extraction sample preparation system is an automated tool for the extraction of DNA and RNA.

Based on the technique, the global sample preparation is categorized into protein preparation, solid-phase extraction, and liquid-liquid extraction. The protein preparation segment accounted for the largest revenue share in 2021 and is expected to remain dominant during the forecast period. The overall market is projected to grow rapidly due to the proteomics field's ongoing innovation. Because contaminants are removed during the extraction procedure from the sample, the repeatability of the data is decreased, which might lead to the loss of proteins. By creating a novel strategy, Babraham Institute researchers upgraded the traditional proteomics sample preparation techniques in July 2022.

The method increases the inclusion of biological proteins that are challenging to collect, increasing the readouts of proteomics. Besides, in 2021, the solid-phase extraction market contributed a sizeable portion of total revenue. The development of procedures in a variety of industries, including food and the environment, is expected to affect market expansion as a whole. For instance, the Waters Corporation announced its plans to release the Extraction+ linked device in October 2022. This device uses solid phase extraction to automate the preparation of forensics, biological, environmental, and food specimens.

Recent Developments:

• In June 2022, to eliminate sample preparation bottlenecks, PerkinElmer introduced the New NGS library preparation kits, NEXTFLEX Small RNA-sew kit v4, NEXTFLEX Rapid XP V2 DNA Seq kit, and PG-Seq Rapid Kit V2.

• In October 2022, to help researchers trace samples throughout the lab workflow, Twist Bioscience introduced the Twist Human Sample ID kit. These kits are simple to incorporate into Twist NGS processes and allow sample identification throughout the lab workflow by enabling tracking from whole blood or purified genomic DNA.

Sample Preparation Market Report Scope:

Sample Preparation Market: Regional Analysis

North America is expected to dominate the market during the forecast period

North America is expected to dominate the global sample preparation market during the forecast period. The growth in the region is attributed to the expansion of research and development (R&D), the introduction of new products, and the concentration of market participants. In the region, the US holds the largest market share, among other countries. The US pharmaceutical industry is most research-intensive. The industry has a substantial financial stake in implementing cutting-edge techniques to boost pipeline development and support advancements in patient care.

The world's pharmaceutical market and 22% of its manufacturing are both accounted for by the United States, according to a March 2022 NCBI article. Additionally, according to the aforementioned source, US pharmaceutical production and sales will increase this year. Therefore, it is projected that the substantial R&D spending in the pharmaceutical industry in the United States will increase demand for sample preparation products and applications.

On the other hand, the Asia Pacific is expected to grow at the highest CAGR during the forecast period. This is a result of sequencing being used more frequently in China and India for a variety of purposes, including the production of personalized medicines. Additionally, it is anticipated that during the projection period, the market would have considerable development potential due to the Asia Pacific region's growing interest in genomics and proteomics research.

Sample Preparation Market: Competitive Analysis

The global sample preparation market is dominated by players like:

• Danaher Corporation
• Agilent Technologies Inc.
• Illumina Inc.
• PerkinElmer Inc.
• QIAGEN N.V
• Bio-Rad Laboratories Inc.
• Norgen Biotek Corporation
• Thermo Fisher Scientific Inc.
• Hamilton Company
• Merck Millipore
• Tecan Group Ltd.
• Promega Corporation
• Sartorius
• Sigma-Aldrich
• Biotage AB
• Waters Corporation 
• Roche Applied Science

The global sample preparation market is segmented as follows:

By Product

• Instruments
• Consumable
• Kits

By Technique

• Protein Preparation
• Solid-phase extraction
• Liquid-liquid extraction

By Application

• Genomics
• Proteomics
• Epigenomics
• Transcriptomics
• Metabolomics
• Others

By End User

• Hospitals
• Diagnostic Centers
• Pharmaceutical and Biotechnology Industry
• Others

By Region

• North America
  • The U.S.
  • Canada
• Europe
  • France 
  • The UK
  • Spain
  • Germany
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC
  • South Africa
  • Rest of Middle East & Africa