Gene Synthesis Market Size, Share, And Growth Report 2032

Gene Synthesis Market Size

The global gene synthesis market size was worth around USD 7.84 billion in 2023 and is predicted to grow to around USD 45.46 billion by 2032 with a compound annual growth rate (CAGR) of roughly 21.6% between 2024 and 2032.

The study provides historical data from 2018 to 2022 along with a forecast from 2024 to 2032 based on revenue (USD billion). The report covers a forecast and an analysis of the gene synthesis market on a global and regional level.

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Gene Synthesis Market: Overview

Gene synthesis is a synthetic biological procedure conducted via in vitro conditions. In gene synthesis, the DNA is duplicated or synthesized with various chemicals. Gene synthesis provides flexibility to the engineered and synthesized target sequences for any kind of downstream application. Unlike DNA replication that occurs in cells or by the use of PCR (Polymerase Chain Reaction), gene synthesis doesn’t require an initial template strand to start the replication process.

The rising number of R&D activities associated with gene synthesis is mainly fueling the growth of the global gene synthesis market. The increasing investments made by leading companies and government of developing countries in gene synthesis, introduction of new and cost-effective gene synthesis technology, growing awareness about the treatment for genetically inherited diseases, and rising prominence of clinical research to understand biological systems at their core molecular levels are some other factors also fueling the global gene synthesis market.

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Gene Synthesis Market: Segmentation

The study provides a decisive view of the gene synthesis market by segmenting it on the basis of method, type, component, application, and region. All the segments have been analyzed based on present and future trends and the market is estimated from 2024 to 2032.

By method, the gene synthesis market includes oligonucleotides and gene assembly. The oligonucleotide segment is sub-segmented into ion semiconductor sequencing, high-throughput array-based gene synthesis technology, phosphoramidite reaction cycle, and nanopore sequencing. Gene assembly segment is further divided into polymerase-based (PCR, OE, polymerase cycling assembly, TBIO, microchip-based multiplex gene synthesis, and others), ligase-based (shotgun ligation, two-step ligation and PCR, ligase chain reaction, and brick-based), and recombinant-based (transformation-associated recombination, SLIC, and biobrick assembly).  

The type segment is divided into custom library synthesis and gene library synthesis. The custom gene synthesis is further sub-segmented into customized coding sequences, RNAi constructs, genomic DNA, cDNA, and others.

Based on component, the market is bifurcated into product and services.

Based on application, the market includes research and development, therapeutics, diagnosis, and others.

Gene Synthesis Market: Report Scope

Gene Synthesis Market: Regional Analysis

The regional segment includes the current and forecast demand for North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa with its further classification into major countries including the U.S., UK, Germany, France, China, Japan, India, Brazil, etc.

By region, North America is expected to dominate the global gene synthesis market in the future, due to the increasing awareness about the growing prevalence of gene-related diseases, rising research on the treatment of these diseases, and the presence of highly developed research infrastructure. The Asia Pacific gene synthesis market is projected to show the highest growth rate in the upcoming years, owing to the growing investments made by companies and government in gene synthesis research, rising number of biopharmaceutical establishments and biotechnology companies, and increasing numbers of gene tests for the diagnosis of gene-related diseases.

Gene Synthesis Market: Competitive Players

Some key players in the global gene synthesis market are:

• ATDBio
• ATUM
• Bioneer Corporation
• BioCat
• Blue Heron Biotech
• Biomatik
• Epoch Life Science
• GENEWIZ
• Eurofins Genomics
• Integrated DNA Technologies
• Genscript
• Kaneka Eurogentec
• ProteoGenix
• OriGene Technologies
• Shanghai Medicilon
• Thermo Fisher Scientific
• Synbio Technologies
• Vigene Biosciences.

The Global Gene Synthesis Market is segmented as follows:

Global Gene Synthesis Market: Method Analysis

• Oligonucleotides
  • Phosphoramidite Reaction Cycle
  • High-Throughput Array-Based Gene Synthesis Technology
  • Ion Semiconductor Sequencing
  • Nanopore Sequencing
• Gene Assembly
  • Polymerase-Based
    • Dual-Asymmetric (DA) PCR
    • Overlap Extension (OE)
    • Polymerase Cycling Assembly
    • Thermodynamically-Balanced Inside-Out (TBIO)
    • Microchip-Based Multiplex Gene Synthesis
    • Others
  • Ligase-Based
    • Shotgun Ligation
    • Two-Step Ligation and PCR
    • Ligase Chain Reaction
    • Brick-Based
  • Recombinant-Based
    • Sequence and Ligation Independent Cloning (SLIC)
    • Transformation-Associated Recombination
    • BioBrick Assembly

Global Gene Synthesis Market: Type Analysis

• Gene Library Synthesis
• Custom Gene Synthesis
  • cDNA
  • Customized Coding Sequences
  • Genomic DNA
  • RNAi Constructs
  • Others

Global Gene Synthesis Market: Component Analysis

• Product
• Services

Global Gene Synthesis Market: Application Analysis

• Research and Development
• Diagnosis
• Therapeutics
• Others

Global Gene Synthesis Market: Regional Analysis

• North America
  • The U.S.
• Europe
  • UK
  • France
  • Germany
• Asia Pacific
  • China
  • Japan
  • India
• Latin America
  • Brazil
• The Middle East and Africa