High-Throughput Screening Market Size, Share, Trends, Growth 2030

High-Throughput Screening Industry Prospect:

The global high-throughput screening market size was worth around USD 18.93 Billion in 2021 and is projected to grow around USD 36.84 Billion by 2030, with a compounded annual growth rate of (CAGR) of roughly 7.82% from 2022 to 2030.

The report analyzes the global high-throughput screening market’s drivers, restraints/challenges, and the effect they have on the demands during the projection period. In addition, the report explores emerging opportunities in the high-throughput screening market.

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High-Throughput Screening (HTS) Market: Overview

High throughput screening is a method that is undertaken to create and design various layouts of drugs. Thus, they are essentially used for carrying out numerous chemical, genetic, and pharmacological tests that help in the overall drug discovery process, be it drug trials, drug design, or other drug interactions. Various steps are involved in this technique including assay development, compound management, target identification, reagent preparation, and high-throughput library screening. In addition, the high-throughput screening technique is extensively used to minimize the overall expense of drug development.

Key Insights

• As per the analysis shared by our research analyst, the global high-throughput screening market is expected to grow annually at a promising CAGR of around 7.82% during the forecast period 2022-2030.
• In terms of revenue, the global high-throughput screening market size was valued at around USD 18.93 Billion in 2021 and is projected to grow to around USD 36.84 Billion, by 2030.
• High-throughput screening (HTS) is basically a drug discovery process that favors automated testing of huge amounts of chemical or biological compounds in order to reach a well-defined biological target. High-throughput screening methods are extensively used in the pharmaceutical industry, making effective use of futuristic automation and robotics for rapid biochemical activity and biological testing of vast amounts of molecules.
• Based on product and service, the services segment is predicted to grow at the fastest CAGR during the forecast period.
• Based on application, the drug discovery segment is projected to grow at the highest CAGR during the forecast period.
• Based on end-user, the contract research organizations segment is expected to have the highest growth CAGR during the forecast period.
• Based on technology, the 3D cell segment is expected to grow at a significant CAGR during the forecast period.
• Based on region, the North American region held the largest market share in 2021 and is further expected to grow at a promising CAGR during the forecast period.

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High-Throughput Screening (HTS) Market: Drivers

Increase in use of high-throughput screening for drug development to increase market demand

There has been a remarkable surge in the use of high-throughput screening for a number of drug development procedures due to its cost-effectiveness, seamless operation, and reduction in the time taken to develop a drug by professionals. More and more people across the globe are contracting various diseases due to a reduction in their immunity due to the adoption of a sedentary lifestyle, making them more susceptible to a range of fatal and serious diseases. Thus, the development of pristinely effective drugs for numerous life-threatening diseases not only for the geriatric population but also for the millennials expansively contributed to the overall growth of the global high-throughput screening market. In addition, rapid technological advancements, rise in automation, and adoption of innovative technologies such as artificial intelligence, machine learning, microplate-free approach, CRISPR-Cas9 & RNAi will significantly contribute to the growth of the market during the forecast period.

High-Throughput Screening (HTS) Market: Restraints

Need for huge capital investment for high-throughput screening restricts the growth of the market to an extent

High-throughput screening involves a series of steps to be undertaken like assay development, reagent preparation, compound screening, target selection, and characterization, and hit validation in secondary assays. A professional can employ any of these processes depending on the time and complexities involved in the target. But mainly each of these processes to be employed can be expensive, making it fairly difficult for multiple academic research laboratories to afford any of these instruments, especially when they have a limited budget.

High-Throughput Screening (HTS) Market: Opportunities

Increasing investments in life science & research activities and growth of pharmaceutical industry offer remunerative opportunities for the market

There has been a notable increase in interest among pharmaceutical companies to actively engage in drug discovery procedures due to a significant surge in demand for superior and effective drugs among people. Governments of emerging economies such as India, China, and Brazil have increased their funding for the adoption of the latest technologies and further increase life science & research activities that provide lucrative opportunities for market players with their diversified healthcare markets, increasing R&D costs, and low labor & raw materials costs. These factors offer lucrative opportunities for the growth of the global high-throughput screening market in the coming years.

High-Throughput Screening (HTS) Market: Challenges

Lack of skilled professionals in underdeveloped and developing countries acts as a major challenge to market growth

High-throughput screening instruments including multimode readers, flow cytometers, and liquid handling systems are utterly intricate technologies that require great expertise while handling. Thus, the lack of skilled professionals required for handling these exquisite instruments poses a formidable challenge to the growth of the market.

High-Throughput Screening (HTS) Market: Segmentation

The global high-throughput screening market is segmented based on product and service, technology, application, end-user, and region.

Based on application, the global market is bifurcated into target identification and validation, drug discovery, primary and secondary screening, toxicology assessment, and others. The drug discovery segment is expected to witness the highest growth rate during the forecast period. The main reason for the growth of this segment is due to a subsequent increase in the number of drug discovery procedures and the rapid adoption of systems & instruments for drug discovery by prominent pharmaceutical and biotechnology companies. Besides, there has been an increase in fundings and investments from the government for the companies to adopt the latest innovative technologies that are effectively required to develop high-quality drugs for the growing demand for new and effective drugs from the people. In addition, the growth of the geriatric population, rapid adoption of a sedentary lifestyle, and lack of physical exercise among people in various countries around the world have made them more vulnerable to life-threatening diseases, driving the need for potent drugs and medications.

HTS technologies are widely implied to determine screen combinatorial chemistry, protein, genomics, and peptide libraries for the recognition of hits. In order to triumph in the screening process, the considerable option of the assay is of paramount importance.

Based on technology, the global market is bifurcated into cell-based assays, lab-on-a-chip, label-free, 2D cell culture, 3D cell culture, and bioinformatics. The 3D cell segment is already seen as futuristic and is expected to grow at a significant CAGR during the forecast period. The main reason behind the growth of this segment is mainly due to the rising focus on effective and revolutionary replacements for animal testing. In addition, there has been a notable surge in the prevalence of chronic diseases, which drives the need for an efficacious and modified drug. Besides, 3D cells portray clear-sighted properties when it comes to testing in the natural environment and other cell-associated operations. This further encourages seamless and wholesome drug design and discovery. In addition, the synergistic effect that is essential for synergies of cell-cell and cell-extracellular matrix (ECM), which can accommodate the articulation of molecules that are present in cell differentiation, is essentially attained in 3D cell cultures.

Recent Developments:

• In November 2022, Particle Works, an innovative company that designs and manufactures innovative particle engineering platforms, announced the launch of its new pioneering platform called the Automated Library Synthesis (ALiS) System. This creative platform favors high-throughput screening of lipid nanoparticle (LNP) formulations and mRNA candidates and automation in the primal stages of drug development. The futuristic ALiS platform is based on microfluidic technology and provides a number of distinctive perks. One of the most prominent benefits is that the software of ALiS platform facilitates walk-away processing of up to 96 unique formulations in an average working day, originating from and bestowing upon covered 96 well plates.
• In April 2022, Twist Bioscience Corporation, a California-based company, announced the launch of its gene-to-antibody production platform called the Twist High Throughput Antibody Production, which helps customers to turn candidate DNA sequences into purified antibodies for numerous screening applications and undertaking therapeutic discoveries.

High-Throughput Screening Market Report Scope:

High-Throughput Screening (HTS) Market: Regional Analysis

North American region is expected to dominate the market during the forecast period

The North American market accounted for the highest global high-throughput screening (HTS) market share and is expected to continue this pattern during the forecast period. The major reason for the growth of the market in this region is mainly due to the increased investment and funding from the government and the robust commercialization of pharmaceutical & biotechnology research. In addition, persistent technological advancements in countries like the US and Canada in this region and extensive application of innovative technologies drive the growth of the market in this region. For instance, pioneering drug development procedures such as 3D cell cultures have gained massive prevalence among companies in this region so as to revolutionize the market with a pristine drug molecule. Furthermore, an increase in the cases of chronic and other diseases, and a surge in investment in pharmaceutical research and development by companies in this region further drive the growth of the market during the forecast period.

High-Throughput Screening (HTS) Market: Competitive Analysis

The global high-throughput screening (HTS) market is dominated by players such as:

• Agilent Technologies Inc
• Danaher Corporation
• Perkinelmer Inc. 
• Thermo Fisher Scientific Inc
• Axxam S.P.A
• Tecan Group Ltd
• Bio-Rad Laboratories Inc.
• Hamilton Company
• Sigma-Aldrich Corporation
• Charles River Laboratories International Inc.
• Merck KGaA
• Corning Incorporated
• BioTek Instruments Inc.
• Aurora Biomed Inc.
• General Electric
• Beckman Coulter Inc.
• Luminex Corporation
• AstraZeneca

The global high-throughput screening (HTS) market is segmented as follows:

By Application

• Target Identification and Validation
• Drug Discovery
• Primary and Secondary Screening
• Toxicology Assessment

By Technology

• Cell-Based Assays
• Lab-On-A-Chip
• Label-Free
• 2D Cell Culture
• 3D Cell Culture
• Bioinformatics

By Product and Service

• Reagents & Assay Kits,
• Instruments,
• Consumables & Accessories
• Software
• Services

By End User

• Pharmaceutical and Biotechnology Industries
• Contract Research Organizations
• Academic and Government Institutes
• Others

By Region

• North America
  • The U.S.
  • Canada
• Europe
  • France 
  • The UK
  • Spain
  • Germany
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC
  • South Africa
  • Rest of Middle East & Africa