Market Size in 2024 | Market Forecast in 2034 | CAGR (in %) | Base Year |
---|---|---|---|
USD 4.89 Billion | USD 8.48 Billion | 5.8% | 2024 |
The global in-vivo toxicology market size was worth around USD 4.89 Billion in 2024 and is predicted to grow to around USD 8.48 Billion by 2034 with a compound annual growth rate (CAGR) of roughly 5.8% between 2025 and 2034.
The report analyzes the global in-vivo toxicology market's drivers, restraints/challenges, and the effect they have on the demands during the projection period. In addition, the report explores emerging opportunities in the in-vivo toxicology industry.
The toxic effect of chemicals is examined on non-human living organisms which are basically called as In-Vivo Toxicology. The cytotoxicity tests actually expose the adverse effects of the drug in living organisms. Before it could be tested on humans, it is tested on organisms or animals to identify the effect of a drug. Many animals are used for testing such as guinea pigs, rodents, rabbits, and others. They are also injected by different ways of exposure. The prominent ones are intravenous, topical, intramuscular, and others.
These tests are done on the isolated organs or parts of the animals. Most hazardous chemical substances actually go through validation in this process even during the early stages of the drug development. The safety evaluation of the drug along with its ranking as a potential drug is done through in-vivo toxicology testing. It includes a total evaluation of all the responses put together like absorption, distribution, metabolism, excretion, dose-response, and threshold response of the drug. Various industries use them on a frequent basis like pharmaceuticals, chemicals, and the food industry. Many research and development organizations also use these kinds of tests on the organisms on a regular basis.
These tests also have the capacity to expose the presence of cultured bacteria or any alien infections in the body. Sometimes, not just the harmful effects of drugs are being exposed, but also the deficiency or toxic properties infested in the organism are identified. The resultant product could be anything ranging from treatment drugs to any agricultural chemicals or even general food additives.
Recent innovations in pharmaceutical and biotechnology industries along with rising focus on personalized medications to propel the market growth
Recent innovations in human cell culture, as well as test systems, instigates an expansion of the market. These tests are predictive, demonstrative, and extremely suitable for screening nanomaterials and airborne materials which makes them a leveraging aspect of drug validation for the companies.
The pharmaceutical and biotechnology industries are keen on developing drug products that have real value rather than some immediate benefits. Hence many innovations in testing methods have been on the rise and serious validation based on its real outcome has been deemed important. This increases the demand for in-vivo toxicology testing in all medical industries thereby propelling market growth considerably.
The focus on bringing the attrition rate of failing molecules in the early stages has become more significant and there is a considerable increase in the leverage of in-vivo testing. An increase in the innovations of animal model testing coupled with rising in the focus on personalized medications also triggers market growth.
There is also an eminent increase in clinical trials which contributes to the growth of the global in-vivo toxicology market. Oncology research along with humanized animal models testing has gained traction which is fueling the market growth in huge proportions. The increase in funding of small biotech firms and small-scale start-ups in pharmaceutical sectors induce market growth as well.
There has also been a considerable rise in the development of toxic substances and dosage testing which has increased the demand for in-vivo testing. Apart from this, this testing has been adopted in various sectors such as pharmaceutical, chemicals, biotechnology firms, cosmetics, and household products.
Availability of alternate methods of testing to animal testing and growing contempt against animal testing hampers the market growth
Animal welfare communities have increased the pressure of contention against animal testing. This has triggered the research scientists and toxicology experts to come up with new methods of alternative testing methods. This impedes market growth to a large extent. In-vitro testing as an alternative has been blooming in recent times and many mainstream companies have adopted that testing method to reduce animal use in toxicology studies. This factor invariably limits the demand for animal model testing proportionally.
The increasing trend of humanized animal model testing in preclinical research provides a lucrative opportunity for market growth
Humanized animal models gained from human cells or tissues have been used rapidly in biotechnology firms. The actual effects of drugs on humans are being estimated by this method which is also deemed to be more precise than any other testing method. They also expose any kind of human-specific infections, and therapies that cure them as well. This factor actually increases the demand and leverage of in-vivo toxicology testing. An increase in oncology research and focus on personalized medicines provide opportunities for the global in-vivo toxicology market expansion.
Government regulations against harming animals for medical testing pose a challenge for the market growth
There has been an increase in the regulations and laws regarding the ethical use of animals in research which instigates the scientists to look for alternative methods of testing. There are also loopholes in animal testing which affect the accuracy and efficacy of the results. All these factors pose a challenge to market growth.
Chronic test type segment in in-vivo testing has increased because of the growing chronic diseases which pose a challenge for the market
In-vivo toxicology is segmented as acute, sub-acute, sub-chronic test types. This has been used rapidly because of the increasing spread of chronic diseases in the geriatric population. This has increased the leverage and demand for in-vivo testing which triggers large-scale employment of the testing equipment and faculties. This poses a challenge for the market to satisfy this massive demand for in-vivo testing.
The global in-vivo toxicology market is segmented based on Product Types, Testing Types, Toxicity Endpoints, Testing Facility, End-User, and region.
Based on Product Types, the global in-vivo toxicology market is divided into Instruments, Animal Models, and Reagents & Kits.
On the basis of Testing Types, the global in-vivo toxicology market is bifurcated into Chronic Toxicity Testing, Sub-Chronic Toxicity Testing, Sub-acute Toxicity Testing, and Acute Toxicity Testing.
By Toxicity Endpoints, the global in-vivo toxicology market is split into Immunotoxicity, Systemic.
In terms of Testing Facility, the global in-vivo toxicology market is categorized into Outsourced, In-House.
By End-User, the global In-Vivo Toxicology market is divided into Academic Institutes, Research Institutes, and CRO’s.
Report Attributes | Report Details |
---|---|
Report Name | In-Vivo Toxicology Market |
Market Size in 2024 | USD 4.89 Billion |
Market Forecast in 2034 | USD 8.48 Billion |
Growth Rate | CAGR of 5.8% |
Number of Pages | 222 |
Key Companies Covered | Charles River Laboratories, The Jackson Laboratory, Envigo, Taconic Biosciences, Janvier Labs, Thermo Fisher Scientific, Danaher Corporation, Waters Corporation, Agilent Technologies, Shimadzu Corporation, Bruker Corporation, PerkinElmer, MerckkgaA, GE Healthcare, Bio-Rad laboratories, genOway, Cyagen Biosciences, GVK BIO, Polygene, Crown Biosciences, Transcure Bioservices, Harbour BioMed.,, and others. |
Segments Covered | By Product Types, By Testing Types, By Toxicity Endpoints, By Testing Facility, By End-User, and By Region |
Regions Covered | North America, Europe, Asia Pacific (APAC), Latin America, The Middle East and Africa (MEA) |
Base Year | 2024 |
Historical Year | 2020 to 2024 |
Forecast Year | 2025 to 2034 |
Customization Scope | Avail customized purchase options to meet your exact research needs. Request For Customization |
In March 2020, GenOway acquired exclusive worldwide rights from Merck for its foundational CRISPR/Cas9 portfolio in the rodent field.
North America is the largest share of the global in-vivo toxicology market. This is due to the presence of major players in the in-vivo toxicology market. There is a growing trend of biomedical research and preclinical activities by CROs happening in this region which makes it the most dominating region for the in-vivo toxicology market. Asia Pacific region also trails as the second-largest share of the market due to the significant growth opportunities for pharmaceutical firms in this region. The growing geriatric population along with qualified researchers and low-cost operations in this region are supporting factors of market growth.
The report provides a company market share analysis to give a broader overview of the key market players. In addition, the report also covers key strategic developments of the market, including acquisitions & mergers, new product launches, agreements, partnerships, collaborations & joint ventures, research & development, and regional expansion of major participants involved in the in-vivo toxicology market on a global and regional basis.
The global in-vivo toxicology market is dominated by players like:
The global in-vivo toxicology market is segmented as follows;
By Product Types
By Testing Types
By Toxicity Endpoints
By Testing Facility
By End-User
By Region
FrequentlyAsked Questions
Leading players in the global in-vivo toxicology market include Charles River Laboratories, The Jackson Laboratory, Envigo, Taconic Biosciences, Janvier Labs, Thermo Fisher Scientific, Danaher Corporation, Waters Corporation, Agilent Technologies, Shimadzu Corporation, Bruker Corporation, PerkinElmer, MerckkgaA, GE Healthcare, Bio-Rad laboratories, genOway, Cyagen Biosciences, GVK BIO, Polygene, Crown Biosciences, Transcure Bioservices, Harbour BioMed.,, among others.
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