Superdisintegrants Market Size, Share, Trends, Growth 2030

Superdisintegrants Industry Prospect:

The global superdisintegrants market size was worth around USD 380 Million in 2021 and is projected to grow around USD 700 Million by 2030, with a compounded annual growth rate (CAGR) of roughly 8.05% from 2022 to 2030.

The report analyzes the global high-throughput screening market’s drivers, restraints/challenges, and the effect they have on the demands during the projection period. In addition, the report explores emerging opportunities in the enterprise data management market.

Request Free Sample

Get more information about this report - Request Free Sample PDF

Superdisintegrants Market: Overview

Superdisintegrants are often defined as modified disintegrants that are added in drug formulations for expediting the disintegration of capsules or tablets into much finer particles. They significantly help in enhancing the overall absorption of the drug along with the solubility of active pharmaceutical ingredients (APIs) in the body. This further resulted in a gradual reduction in disintegration time, thereby ameliorating their efficacy. They are also used at lower levels in the form of solid dosage, most particularly ranging between 1 - 10% by weight relative to the aggregate weight of the dosage unit. Currently, they are present and accessible in natural as well as synthetic variants and are widely utilized in various therapeutic areas, including neurological, gastrointestinal, cardiovascular, infectious, hematological diseases, and inflammatory diseases.

Key Insights

• As per the analysis shared by our research analyst, the global superdisintegrants market is expected to grow annually at a promising CAGR of around 8.05% during the forecast period 2022-2030.
• In terms of revenue, the global superdisintegrants market size was valued at around USD 380 million in 2021 and is projected to grow to around USD 700 million, by 2030.
• Superdisintegrants are defined as substances that are included within the tablet formulations to favor the breakdown of large and compacted mass into smaller particles so that it becomes much more soluble. These substances promote the rapid disintegration and dissolution of medications. Superdisintegrants may be classified as sodium starch glycolate, ion exchange resins, croscarmellose sodium, crospovidone, and others.
• Based on product, the crospovidone segment held the largest market share in 2021 and is also predicted to grow at the fastest CAGR during the forecast period.
• Based on formulation, the tablets segment held the largest market share in 2021 and is further projected to be the largest market during the forecast period.
• Based on therapeutic area, the neurological diseases segment held the dominating market share in 2021 and is further predicted to cite a significant CAGR during the forecast period.
• Based on region, the North American region held the dominating market share in 2021 and is further predicted to grow exponentially at a promising CAGR during the forecast period.

Request Free Sample

To know more about this report, request a sample copy.

Superdisintegrants Market: Drivers

Surge in the adoption of ODTs and rise in chronic diseases among people drive market growth

There has been a remarkable surge in the number of chronic diseases among people and a rise in the geriatric population across the globe that significantly contributes to the growth of the global superdisintegrants market. Besides, an increase in the popularity of orally disintegrating tablets (ODTs) in both nutraceutical and pharmaceuticals to treat patients suffering from dysphagia and other related conditions boosts the growth of the market. In addition, superdisintegrants are extensively used in the production of ODTs for making antidepressant, antipsychotic, antimigraine, and sedative drugs. Furthermore, remarkable growth in healthcare expenditure, sedentary lifestyle among millennials, surge in pediatric patients, and growing burden of various neurological disorders among people further drive the growth of the market during the forecast period.

Superdisintegrants Market: Restraints

High cost of treatments, diagnosis, and medication may restrict the growth of the market

Healthcare expenditures have been on the rise in the last couple of years, which makes it extremely difficult for low-income individuals to undertake necessary treatments and diagnoses. Thus, extortionate costs of treatments and medications in developed countries impede the growth of the market to an extent. In addition, a lack of awareness about effective and efficient drugs among people further restricts the growth of the market.

Superdisintegrants Market: Opportunities

Increase in R&D activities for new drug development offers remunerative opportunities for market

There has been a rapid surge in the prevalence of research and development activities among various pharmaceutical and nutraceutical companies for the development of better and more efficient drugs for people. Thus, persistent developments in technology and innovations of novel formulations for drug development create ample opportunities for the global superdisintegrants market. Besides, an increase in the acceptance of superdisintegrants across the globe due to its impeccable perks such as productive compressibility, enhanced bioavailability, and better compatibility along with the growing popularity of telemedicine create ample opportunities for the growth of the superdisintegrants industry during the forecast period.

Superdisintegrants Market: Challenges

Increase in concerns about the efficacy and quality of drugs may act as a major challenge to market growth

In spite of coping with the extensive application of superdisintegrants in pharmaceuticals, the industry is likely to face adverse issues regarding the quality and efficacy of drugs that might be critical to patients. This is because potential variations in superdisintegrant production might massively affect the performance of the drug apart from its dire quality attributes. Besides, ensuring full-scale transparency in supply chain activities and assuring streamlined operations in low-cost countries is difficult which acts as a challenge to the growth of the market.

Superdisintegrants Market: Segmentation

The global superdisintegrants market is segmented based on product, formulation, therapeutic area, and region.

Based on product, the global market is bifurcated into croscarmellose sodium, crospovidone, sodium starch glycolate, ion exchange resins, modified cellulose, and others. The crospovidone segment held the largest market share in 2021 and is also predicted to grow at the fastest CAGR during the forecast period. This is mainly attributed to the impeccable ability of crospovidone to balance the vague state of drugs due to restrictions in drug recrystallization. In addition, crospovidone has an expeditious solidification rate which appreciably assists in drug discovery processes. In addition, crospovidone has a remarkable dissolution and disintegration-enhancing effect, which is essentially used in the preparation of different capsules, tablets, and granules. These factors are predicted to drive the growth of the segment during the forecast period.

Based on formulation, the global market is bifurcated into tablets, capsules, and mouth-dissolving films. The tablets segment held the largest market share in 2021 and is further predicted to cite a promising CAGR during the forecast period. The major reason for the growth of this segment is its increased stability and inexpensive manufacturing costs compared to other forms of dosage such as mouth-dissolving films and capsules. In addition, tablets have a longer shelf life and their dosage can be easily tracked accurately. Besides, tablets have a rapidly dissolving dosage form that is subsequently recognized by the FDA and are further enlisted in authorized drug products that have essential therapeutic equivalence considerations. These factors drive the growth of the segment during the forecast period. Various disintegrants that are used in making multifunctional tablet formulations include cellulose, starch, crospovidone, and others.

Recent Developments:

• In January 2022, DFE Pharma, a Germany-based innovative manufacturer of excipients, announced that they have added a new maize starch range in its Nutroféli excipients portfolio supplements in the rapidly evolving nutraceuticals industry. Nutraceutical products have gained massive traction in the past couple of years ever since the pandemic hit billions of people across the globe. Thus, consumers are incessantly becoming increasingly informed about self-care, well-being, and disease prevention. The German multinational company, with the launch of starches, envisions meeting the intrinsic needs of nutraceutical companies for superior quality, whilst ensuring timely delivery and supply. In addition, the maize starch portfolio gives enough options to companies to meet their formulation requirements as disintegrants, fillers, and binders, apart from other applications. This is mainly because starches essentially behave as diluents, disintegrants, and binders in most tablets and capsules, as an effective alternative to gelatine in soft gels, which makes it an utterly adaptable excipient.
• In July 2021, Omya International AG, a dominant Switzerland-based supplier of minerals, announced the launch of its two new excipients, namely Omyanutra 300 DC and Omyanutra 300 Flash. The former notably facilitate free-flowing granules and enables the tablet to be compacted, while the latter comes with a superdisintegrant that is capable of expediting disintegration in oral and fast-dissolving tablets, irrespective of the rigidity of the solid dosage form. Both these products provide a much superior compactability when compared to standard excipients such as microcrystalline cellulose and lactose.

Superdisintegrants Market: Report Scope:

Superdisintegrants Market: Regional Analysis

North American region is expected to dominate the market during the forecast period

The North American region held the largest global superdisintegrant market share in 2021 and is further expected to cite a promising CAGR during the forecast period. The major reason for the growth of the market in this region is the significant surge in demand for generic drugs as there has been an increase in the cases of chronic diseases and a rise in the geriatric population in the region. For instance, there has been a remarkable surge in the number of cases of Alzheimer’s disease and migraines in countries like the U.S. Thus, orally disintegrating tablets play a major role in providing effective treatment for various neurological disorders among people in this region. Besides, persistent technological advancements and innovations in the manufacturing of superdisintegrants, a rise in R&D expenditure among pharmaceutical players, and an increase in financial support from the government for the development of novel drug development procedures and innovative oral dosage forms in the region drive the growth of the superdisintegrants industry during the forecast period.

Superdisintegrants Market: Competitive Analysis

The global superdisintegrants market is dominated by players including:

• DFEPharma
• JRSPHARMA
• Merck KGaA
• Avantor Inc.
• Corel PharmaChem
• DuPont
• Asahi Kasei Corporation
• Dow
• BASF SE
• Ashland
• NIPPO SODA CO. LTD.
• RoquetteFreres

The global superdisintegrants market is segmented as follows:

By Product

• Croscarmellose Sodium,
• Crospovidone
• Sodium Starch Glycolate
• Ion Exchange Resins
• Modified Cellulose
• and Others

By Formulation

• Tablet
• Capsules
• Mouth-Dissolving Film

By Therapeutic Area

• Oncology
• Neurology
• Cardiology
• Infectious Diseases

By Region

• North America
  • The U.S.
  • Canada
• Europe
  • France 
  • The UK
  • Spain
  • Germany
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC
  • South Africa
  • Rest of Middle East & Africa