Humanized Mouse and Rat Model Market Size, Share, Growth, Forecast 2032

Experimental animals referred to as humanized mouse and rat models have undergone genetic modification or engrafting with human cells, tissues, or organs in order to replicate physiological processes, immune responses, and the pathogenesis of diseases. Inbiomedical research utilizes these models as invaluable instruments for investigating human maladies, evaluating therapeutic interventions, and comprehending biological processes that are unique to humans.

Constant progress in genetic engineering methodologies, exemplified by the utilization of CRISPR-Cas9 technology, facilitates the modification of mouse and rat genomes in a more accurate and efficient manner, thereby enabling the development of humanized models. Enhanced techniques for engrafting human tissues or cells into these animals also contribute to the expansion of the market.

The global humanized mouse and rat model market size was worth around USD 261.03 million in 2023 and is predicted to grow to around USD 446.27 million by 2032.

The global humanized mouse and rat model market with a compound annual growth rate (CAGR) of roughly 6.14% between 2024 and 2032.

North America dominated the global humanized mouse and rat model market in 2018. Increasing focus to develop humanized mouse and rat models for various therapeutic applications, increasing investment for research on humanized models, increasing demand for personalized medicine, presence of major market players, and presence of developed infrastructure are the factors attributing to the growth in this region. Europe was the second largest market in terms of revenue share.

Major players in humanized rat models are Yecuris Corporation, Hera BioLabs, and Horizon Discovery Group plc. Major players in humanized mouse models are Champions Oncology, Inc., Transgenic, Inc., Crown Bioscience, Inc., AXENIS S.A.S, inGenious Targeting Laboratory, Vitalstar Biotechnology Co., Ltd., Hera BioLabs, Harbour Antibodies BV, Charles River Laboratories, genOway, S.A., Horizon Discovery Group plc, Taconic Biosciences, Inc., and The Jackson Laboratory among others.